Emergency services have been called to crash involving multiple vehicles and a motorcycle on Forest Road, on the outskirts of Newport.
Police and the Isle of Wight Ambulance service have been called to the incident which happened at 12.21pm today (Monday).
Police say two cars, a van and a motorcyclist are involved.
Forest Road between its junction with Parkhurst Road and Gunville Road has been closed. Diversions are in place via Newport, Carisbrooke and Gunville.
Police say minor injuries have been reported.
*Police have now said five vehicles in total have been involved. Work is continuing to clear the road.
**The road has now re-opened.