Emergency crews are at a crash on Medina Way in Newport, near its junction with Lonsdale Road.
Traffic is being diverted behind HMP Isle of Wight.
Hampshire Constabulary was called to a three vehicle collision, including a bus, on Parkhurst Road at 8.34am.
Police says there were seven “minor” injuries and one more serious injury. One person has been taken to St Mary’s Hospital.
The road has now reopened.
*Southern Vectis’ operations manager said: