Friends star Matthew Perry could not go through with a scene in which Chandler cheated on Monica, according to an actress on the episode.
Lisa Cash, who was due to play the part, said Perry was worried viewers would "never forgive" his character for sleeping with another woman.
She said she rehearsed for two days to play a Las Vegas hotel worker bringing room service to Chandler.
Upset that Monica took lunch with her ex-boyfriend, the script had Chandler pouring his heart out and then sleeping with Cash's character.
However, Perry is said to have got cold feet and spoke out to get rid of the season five scene.
Cash told NBC News:
"We had rehearsed it and everything, and then the day before we were shooting in front of a live audience I was told Chandler went to the writers and said the audience will never forgive him for cheating on Monica."
She said the whole course of Friends might have been altered had the scene gone ahead as planned.
"The Ross and Rachel (David Schwimmer and Jennifer Aniston) thing, 'They were on a break', but this wouldn't have been on a break," said Cash.
"This would have been a decision he would have made while they were together."
She added: "I think it would have really changed how the audience would have (viewed) Chandler and that whole thing. I don't know if they could have survived it."
Cash did end up getting her moment on the show and instead appeared as a flight attendant in the same episode - The One in Vegas: Part I.
Perry's funeral took place last week in LA, with his famous co-stars all in attendance for the ceremony of about 20 people.
The 54-year-old died on 28 October from apparent drowning, but initial post-mortem results were reportedly inconclusive so more investigations were ordered.
(c) Sky News 2023: Matthew Perry couldn't go through with Friends scene in which Chandler cheated on Monica,