Emergency services are at a crash on Fairlee Road in Newport.
Two ambulances, police and one fire engine from Ryde are in attendance.
The incident is said to have involved a car and a motorcycle.
It's happened at the site of the main festival entrance, near the 'HP' house.
There are delays in the area.
Updated
A police spokesperson said:
“At 4.36pm we were called to Fairlee Road, Newport, following reports of a collision involving a car and a motorbike.
“Injuries were reported to us.
“The road was closed, but it has now reopened.”