Donald Trump has chosen vaccine sceptic Robert F Kennedy Jr as his new health secretary.
The news was announced by Donald Trump Jr on X, before the president-elect confirmed the appointment just moments later.
Former Democrat RFK Jr, the nephew of former president John F Kennedy, had been running as an independent presidential candidate but dropped out of the race and endorsed Mr Trump in August.
In return for Mr Kennedy's support during the election, President-elect Trump pledged to give him a "big role" - and RFK Jr's preference for the health position was widely reported.
The health and human services (HHS) department includes the Food and Drug Administration, the Centers for Disease Control and Prevention, Medicare, Medicaid and the National Institutes of Health.
RFK Jr will "restore these Agencies to the traditions of Gold Standard Scientific Research, and beacons of Transparency, to end the Chronic Disease epidemic, and to Make America Great and Healthy Again," the president-elect wrote on X.
Mr Trump added: "For too long, Americans have been crushed by the industrial food complex and drug companies who have engaged in deception, misinformation, and disinformation when it comes to Public Health.
"The Safety and Health of all Americans is the most important role of any Administration."
Mr Kennedy is a known vaccine sceptic who has repeated misinformation on multiple occasions, including the discredited theory that childhood immunisations cause autism.
The RFK Jr-led health department will "play a big role in helping ensure that everybody will be protected from harmful chemicals, pollutants, pesticides, pharmaceutical products, and food additives that have contributed to the overwhelming Health Crisis in this Country," the president-elect added.
Earlier, his son Donald Trump Jr was the first to confirm the appointment, writing on X: "Robert F Kennedy Jr will be The Secretary of Health and Human Services! Promises Made Promises Kept."
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RFK Jr's position will need to be confirmed with a Senate vote - but even with the chamber under Republican control, his appointment may face opposition because of his views on health issues.
Before Mr Trump announced his choice, Mr Kennedy had already claimed the new president would push to remove fluoride from drinking water on his first day in office. The addition of the compound has been cited as helping to improve dental health.
The department RKF Jr is hoping to oversee has more than 80,000 employees across the United States.
(c) Sky News 2024: RFK Jr chosen as Donald Trump's health secretary